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Which of the following is specific to type 2 diabetes?


A) It is caused when the pancreas is not producing insulin.
B) It is likely due to an environmental agent, perhaps a virus, that causes cytotoxic T cells to destroy islets.
C) It is treated with insulin injections and pancreatic transplants.
D) It is dangerous due to the risk of acidosis, coma, and death.
E) It is often caused by obesity.

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Which gland decreases in size as we age and could be responsible for a decreased immune response?


A) thymus
B) thyroid
C) parathyroid
D) pancreas
E) testes in males; ovaries in females

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List and explain the role of the main growth factors.

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Granulocyte-macrophage colony-stimulatin...

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Which of the following is an effect of the hormone testosterone?


A) accumulation of a fat layer beneath the skin
B) pelvic girdle grows wider
C) breast development
D) egg maturation and menstrual cycle control
E) growth of hair and muscular tissue

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Which of the following is mismatched?


A) leptin-signals satiety
B) platelet-derived growth factor-increases the size of platelets
C) nerve growth factor-promotes growth of nerves
D) epidermal growth factor-stimulates growth of skin
E) granulocyte and macrophage colony-stimulating factor-helps stem cells decide on blood cell production

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Which of the following glands and associated disorders is mismatched?


A) adrenal cortex-bronzing of skin, no increase in blood glucose levels in response to stress, dehydration, and death
B) pineal gland-decrease in T cell immune function
C) parathyroid glands-drop in blood calcium level and tetany (muscles shake)
D) ovaries-alteration in menstrual cycle and change in secondary sex characteristics
E) adult thyroid-low pulse rate and body temperature and lethargy

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What is the exocrine role of the pancreas?


A) The pancreas secretes digestive juices into the small intestine.
B) The pancreas secretes digestive juices into the stomach.
C) The pancreas secretes digestive juices into the large intestine.
D) The pancreas produces insulin that is secreted into the bloodstream.
E) The pancreas produces glucagon that is taken up by the liver.

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What is the role of the epidermal growth factors?


A) stimulate the healing of wounds
B) increase the number of fibroblasts
C) increase the number of smooth muscle cells
D) increase the chances of developing a wound
E) form into different types of white blood cells

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When Lauren reached the age of puberty, she did not undergo the expected changes. Today, at 17, she has still not undergone puberty. What endocrine gland could be the issue?


A) posterior pituitary
B) parathyroid
C) thymus
D) pancreas
E) adrenal cortex

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What are the chemical signals that act between two individuals of the same species?


A) pheromones
B) first messenger
C) second messenger
D) growth factors
E) None of the answer choices are chemical signals that communicate between two individuals of the same species.

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Which body system consists of glands and tissues that secrete hormones?


A) nervous system
B) digestive system
C) respiratory system
D) circulatory system
E) endocrine system

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What is the role of the second messenger?


A) to set in motion the enzyme cascade
B) convey information between two individuals of the same species
C) binds to the cell surface
D) to activate the third messenger
E) None of the answer choices are functions of the second messenger.

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What is "tetany"?


A) continuous muscle contractions due to high blood calcium
B) continuous muscle contractions caused by low blood calcium
C) the random contractions of fibers in a muscle that keep a person upright
D) inability to function caused by low blood sugar due to diabetes
E) ultimate muscle fatigue where the oxygen debt exceeds all ATP available

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Which of the following is the pathway produced in the adrenal glands in response to long-term stress?


A) hypothalamus (ACTH-releasing hormone) → anterior pituitary (ACTH) → adrenal cortex (glucocorticoids)
B) hypothalamus (ACTH-releasing hormone) → anterior pituitary (ACTH) → adrenal medulla (epinephrine and norepinephrine)
C) anterior pituitary (ACTH) → hypothalamus (ACTH-releasing hormone) → adrenal medulla (epinephrine and norepinephrine)
D) adrenal cortex (glucocorticoids) → anterior pituitary (ACTH) → hypothalamus (ACTH-releasing hormone)
E) adrenal medulla (epinephrine and norepinephrine) → hypothalamus (ACTH-releasing hormone) → anterior pituitary (ACTH)

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Which of the following hormonal disorders is mismatched?


A) acromegaly-overproduction of GH in adult
B) pituitary dwarf-too little GH produced during childhood
C) Cushing syndrome-oversecretion of ACTH due to an adrenal cortex tumor
D) diabetes-either the pancreas produces too much insulin or liver and muscle cells have too many receptors
E) goiter-thyroid is unable to produce thyroxine due to too little iodine in diet

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Absence of the parathyroid hormone causes


A) lethargy and hair loss.
B) tetany.
C) sleepiness.
D) mental retardation.
E) cretinism.

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College students are notorious for having a reversed day-night schedule. They stay up all night and sleep during the day. This alteration changes what hormone levels?


A) melatonin
B) leptin
C) growth hormone
D) testosterone in males; estrogen in females
E) prostaglandins

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Which disease results when the adrenal cortex produces too much hormone?


A) diabetes insipidus
B) diabetes mellitus
C) Cushing syndrome
D) Addison disease
E) myxedema

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Glucagon stimulates the liver to take up glucose in order to store it as glycogen.

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Type 1 diabetes is the most common form of diabetes in the United States.

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