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During what renal process are molecules selectively removed from the tubule lumen, moved into the interstitial space, and removed from the kidneys by the peritubular capillaries and the vasa recta?


A) reabsorption
B) excretion
C) absorption
D) filtration
E) secretion

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(Clearance / Secretion) is a measure of the volume of plasma from which a substance is completely removed by the kidneys.

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In tubuloglomerular feedback, an increase in glomerular filtration rate would increase the______ , thereby stimulating the release of a paracrine factor from the macula densa that would______


A) flow of tubular fluid : constrict the efferent arteriole
B) afferent arteriolar pressure : constrict the afferent arteriole
C) afferent arteriolar pressure : increase filtrate flow
D) flow of tubular fluid : constrict the afferent arteriole
E) flow of tubular fluid : dilate the afferent arteriole

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Filtration fraction is calculated as glomerular filtration rate × plasma concentration of a solute.

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Which of the following forms the filtration barrier?


A) capillary endothelial cells only
B) podocytes only
C) basement membrane only
D) both capillary endothelial cells and basement membrane
E) capillary endothelial cells, basement membrane, and podocytes

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Although some of the mechanisms are the same, the functions of the proximal and distal tubules are quite different. Compare and contrast the structural differences between epithelial cells in the proximal and distal tubes.

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Overall, the structural differences betw...

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What are the conical sections of the renal medulla called?


A) renal pyramids
B) renal cortex
C) minor calyces
D) renal pelvis
E) major calyces

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What capillaries come off of the efferent arterioles associated with cortical nephrons?


A) arcuate
B) glomerulus
C) lobular
D) vasa recta
E) peritubular

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The micturition reflex is activated by the stretch of the bladder, which activates what?


A) parasympathetic afferents
B) sympathetic afferents
C) somatic afferents
D) stretch receptors
E) parasympathetic efferents

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Which layer of the filtration barrier in Bowman's capsule is the primary barrier to the movement of protein from the capillary?


A) macula densa
B) granular cell
C) basement membrane
D) endothelial cell
E) epithelial cell

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Which of the following can increase the filtered load of a particular solute?


A) increasing the rate of secretion
B) decreasing the rate of excretion
C) increasing the glomerular filtration rate
D) increasing the rate of reabsorption
E) decreasing the plasma concentration of the solute

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If the amount of a solute excreted in the urine per minute is less than the filtered load, then that solute had to have been (reabsorbed / secreted) in the renal tubules.

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The distal tubule functions as a mass absorber.

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Despite being less than 1% of body weight, the kidneys receive what percent of resting cardiac output?


A) 35%
B) 20%
C) 1%
D) 15%
E) 5%

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Most filtered solutes and water are reabsorbed in what region?


A) collecting duct
B) proximal tubule
C) distal tubule
D) loop of Henle
E) Bowman's capsule

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The macula densa consists of specialized cells of the distal tubule epithelium.

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The clearance of what substance provides the best estimate of renal blood flow rate?


A) creatine
B) inulin
C) glucose
D) sodium
E) PAH

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What is the process whereby protein -free plasma moves by bulk flow from the glomerulus into Bowman's capsules?


A) glomerular filtration
B) absorption
C) excretion
D) reabsorption
E) secretion

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Which of the following describes elimination of urine from the body?


A) micturition
B) secretion
C) reabsorption
D) filtration
E) excretion

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Which of the following is NOT a mechanism whereby glomerular filtration rate is regulated?


A) mesangial cell contraction
B) granular cell contraction
C) myogenic regulation
D) sympathetic nervous system
E) tubuloglomerular feedback

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