Question 1

When considering hemolytic anemia,which statement is true regarding the occurrence of jaundice?

Accepted Answer

A)   Erythrocytes are destroyed in the spleen.
B)   Heme destruction exceeds the liver's ability to conjugate and excrete bilirubin.
C)   The patient has elevations in aspartate transaminase (AST)  and alanine transaminase (ALT) .
D)   The erythrocytes are coated with an immunoglobulin.

Question 2

What is the most common cause of iron deficiency anemia (IDA) ?

Accepted Answer

A)   Decreased dietary intake
B)   Chronic blood loss
C)   Vitamin deficiency
D)   Autoimmune disease

Question 3

What is the most common pathophysiologic process that triggers aplastic anemia (AA) ?

Accepted Answer

A)   Autoimmune disease against hematopoiesis by activated cytotoxic T (Tc)  cells
B)   Malignancy of the bone marrow in which unregulated proliferation of erythrocytes crowd out other blood cells
C)   Autoimmune disease against hematopoiesis by activated immunoglobulins
D)   Inherited genetic disorder with recessive X-linked transmission

Question 4

Which type of anemia is characterized by fatigue,weakness,and dyspnea,as well as conjunctiva of the eyes and brittle,concave nails?

Accepted Answer

A)   Pernicious
B)   Iron deficiency
C)   Aplastic
D)   Hemolytic

Question 5

Match the phrases with the corresponding terms.Options may be used more than once.
-Sideroblastic anemia

Accepted Answer

A)  Normocytic-normochromic anemia
B)  Microcytic-hypochromic anemia
C)  Macrocytic-normochromic anemia

Question 6

Treatment for polycythemia vera involves which of the following?

Accepted Answer

A)   Therapeutic phlebotomy and radioactive phosphorus
B)   Restoration of blood volume by plasma expanders
C)   Administration of cyanocobalamin
D)   Blood transfusions

Question 7

Which medications are associated with an intermediate increase in a person's risk for developing aplastic anemia? (Select all that apply.)

Accepted Answer

A)   Penicillin
B)   Chloramphenicol (Chloromycetin) 
C)   Phenytoin (Dilantin) 
D)   Trimethoprim-sulfamethoxazole (Bactrim) 
E)   Thiazides

Question 8

Erythrocyte life span of less than 120 days,ineffective bone marrow response to erythropoietin,and altered iron metabolism describe the pathophysiologic characteristics of which type of anemia?

Accepted Answer

A)   Aplastic
B)   Sideroblastic
C)   Anemia of chronic disease
D)   Iron deficiency

Question 9

Considering sideroblastic anemia,what would be the expected effect on the plasma iron levels?

Accepted Answer

A)   Plasma iron levels would be high.
B)   Levels would be low.
C)   Levels would be normal.
D)   Levels would be only minimally affected.

Question 10

What is the treatment of choice for pernicious anemia (PA) ?

Accepted Answer

A)   Cyanocobalamin by oral intake
B)   Vitamin B12 by injection
C)   Ferrous fumarate by Z-track injection
D)   Folate by oral intake

Question 11

The underlying disorder of which anemia is a result of the defective secretion of the intrinsic factor,which is essential for the absorption of vitamin B₁₂?

Accepted Answer

A)   Microcytic
B)   Pernicious
C)   Hypochromic
D)   Hemolytic

Question 12

What is the primary cause of the symptoms of polycythemia vera?

Accepted Answer

A)   Decreased erythrocyte count
B)   Destruction of erythrocytes
C)   Increased blood viscosity
D)   Neurologic involvement

Question 13

Which diseases are commonly associated with anemia of chronic disease? (Select all that apply.)

Accepted Answer

A)   Rheumatoid arthritis
B)   Acquired immunodeficiency syndrome (AIDS) 
C)   Polycythemia vera
D)   Systemic lupus erythematosus
E)   Chronic hepatitis

Question 14

Which of the following is classified as a megaloblastic anemia?

Accepted Answer

A)   Iron deficiency
B)   Pernicious
C)   Sideroblastic
D)   Hemolytic

Question 15

Clinical manifestations of mild-to-moderate splenomegaly and hepatomegaly,bronze-colored skin,and cardiac dysrhythmias are indicative of which anemia?

Accepted Answer

A)   Iron deficiency
B)   Pernicious
C)   Sideroblastic
D)   Aplastic

Question 16

Which of the following describes how the body compensates for anemia?

Accepted Answer

A)   Increasing rate and depth of breathing
B)   Decreasing capillary vasoconstriction
C)   Hemoglobin holding more firmly onto oxygen
D)   Kidneys releasing more erythropoietin

Question 17

How is the effectiveness of vitamin B₁₂ therapy measured?

Accepted Answer

A)   Reticulocyte count
B)   Serum transferring
C)   Hemoglobin
D)   Serum vitamin B12

Question 18

Which statement about folic acid is false?

Accepted Answer

A)   Folic acid absorption is dependent on the enzyme folacin.
B)   Folic acid is stored in the liver.
C)   Folic acid is essential for RNA and DNA synthesis within erythrocytes.
D)   Folic acid is absorbed in the upper small intestine.

Question 19

What causes the atrophy of gastric mucosal cells that result in pernicious anemia?

Accepted Answer

A)   Erythrocyte destruction
B)   Folic acid malabsorption
C)   Vitamin B12 malabsorption
D)   Poor nutritional intake

Exam 28: Alterations of Erythrocyte Function

Which diseases are commonly associated with anemia of chronic disease? (Select all that apply.)

Correct Answer
verified

What is the most common pathophysiologic process that triggers aplastic anemia (AA) ?

Correct Answer
verified

Which statement about folic acid is false?

Correct Answer
verified

What is the most common cause of iron deficiency anemia (IDA) ?

Correct Answer
verified

Clinical manifestations of mild-to-moderate splenomegaly and hepatomegaly,bronze-colored skin,and cardiac dysrhythmias are indicative of which anemia?

Correct Answer
verified

When considering hemolytic anemia,which statement is true regarding the occurrence of jaundice?

Correct Answer
verified

Erythrocyte life span of less than 120 days,ineffective bone marrow response to erythropoietin,and altered iron metabolism describe the pathophysiologic characteristics of which type of anemia?

Correct Answer
verified

What causes the atrophy of gastric mucosal cells that result in pernicious anemia?

Correct Answer
verified

The underlying disorder of which anemia is a result of the defective secretion of the intrinsic factor,which is essential for the absorption of vitamin B₁₂?

Correct Answer
verified

Considering sideroblastic anemia,what would be the expected effect on the plasma iron levels?

Correct Answer
verified

Which medications are associated with an intermediate increase in a person's risk for developing aplastic anemia? (Select all that apply.)

Correct Answer
verified

How is the effectiveness of vitamin B₁₂ therapy measured?

Correct Answer
verified

Which of the following is classified as a megaloblastic anemia?

Correct Answer
verified

Which type of anemia is characterized by fatigue,weakness,and dyspnea,as well as conjunctiva of the eyes and brittle,concave nails?

Correct Answer
verified

What is the primary cause of the symptoms of polycythemia vera?

Correct Answer
verified

What is the treatment of choice for pernicious anemia (PA) ?

Correct Answer
verified

Treatment for polycythemia vera involves which of the following?

Correct Answer
verified

Match the phrases with the corresponding terms.Options may be used more than once. -Sideroblastic anemia

Correct Answer
verified

Which of the following describes how the body compensates for anemia?

Correct Answer
verified

Exam 28: Alterations of Erythrocyte Function

Which diseases are commonly associated with anemia of chronic disease? (Select all that apply.)

Correct AnswerverifiedShow Answer

What is the most common pathophysiologic process that triggers aplastic anemia (AA) ?

Correct AnswerverifiedShow Answer

Which statement about folic acid is false?

Correct AnswerverifiedShow Answer

What is the most common cause of iron deficiency anemia (IDA) ?

Correct AnswerverifiedShow Answer

Clinical manifestations of mild-to-moderate splenomegaly and hepatomegaly,bronze-colored skin,and cardiac dysrhythmias are indicative of which anemia?

Correct AnswerverifiedShow Answer

When considering hemolytic anemia,which statement is true regarding the occurrence of jaundice?

Correct AnswerverifiedShow Answer

Erythrocyte life span of less than 120 days,ineffective bone marrow response to erythropoietin,and altered iron metabolism describe the pathophysiologic characteristics of which type of anemia?

Correct AnswerverifiedShow Answer

What causes the atrophy of gastric mucosal cells that result in pernicious anemia?

Correct AnswerverifiedShow Answer

The underlying disorder of which anemia is a result of the defective secretion of the intrinsic factor,which is essential for the absorption of vitamin B₁₂?

Correct AnswerverifiedShow Answer

Considering sideroblastic anemia,what would be the expected effect on the plasma iron levels?

Correct AnswerverifiedShow Answer

Which medications are associated with an intermediate increase in a person's risk for developing aplastic anemia? (Select all that apply.)

Correct AnswerverifiedShow Answer

How is the effectiveness of vitamin B₁₂ therapy measured?

Correct AnswerverifiedShow Answer

Which of the following is classified as a megaloblastic anemia?

Correct AnswerverifiedShow Answer

Which type of anemia is characterized by fatigue,weakness,and dyspnea,as well as conjunctiva of the eyes and brittle,concave nails?

Correct AnswerverifiedShow Answer

What is the primary cause of the symptoms of polycythemia vera?

Correct AnswerverifiedShow Answer

What is the treatment of choice for pernicious anemia (PA) ?

Correct AnswerverifiedShow Answer

Treatment for polycythemia vera involves which of the following?

Correct AnswerverifiedShow Answer

Match the phrases with the corresponding terms.Options may be used more than once. -Sideroblastic anemia

Correct AnswerverifiedShow Answer

Which of the following describes how the body compensates for anemia?

Correct AnswerverifiedShow Answer

Correct Answer
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