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Typical eukaryotic genomes are composed of ________ chromosomes.


A) multiple linear
B) multiple circular
C) a single circular
D) a single linear
E) both linear and circular

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A chemical is reported to inhibit bacterial replication. Bacterial cells are placed in medium with all nutrients necessary for replication. The chemical is added to the culture, and after a half hour an extract of the DNA is prepared. A significant percentage of the DNA is in pieces about 1000 to 2000 bases in length. The results are consistent with the chemical blocking the function of DNA ligase.

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During elongation, a charged tRNA first enters the ribosomal ________ site and then moves into the ________ site.


A) A; E
B) P; A
C) P; E
D) A; P
E) E; A

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Which of the following is NOT a characteristic of both DNA and RNA polymerases?


A) directionality of synthesis
B) energy is provided by pyrophosphate
C) hydrogen bonding of complementary nucleotides
D) requirement for an initiation signal
E) requirement for a primer

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The phenotype of an organism is its set of (genes/traits/chromosomes).

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Which of the following types of plasmids allows a bacterial cell to kill its competitors?


A) virulence plasmids
B) fertility plasmids
C) bacteriocin plasmids
D) resistance plasmids
E) cryptic plasmids

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The Ames test demonstrates that a chemical is


A) carcinogenic.
B) carcinogenic in Salmonella.
C) mutagenic in Salmonella.
D) carcinogenic in humans.
E) mutagenic in humans.

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The (leading/lagging/replicating) strand is the DNA strand that is synthesized continuously during DNA replication.

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The chemical 5-bromouracil mimics the chemical structure of thymine, making it a(n) (analog/nucleotide/precursor) of thymine.

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DNA, which is negatively charged, wraps around positively charged histones as part of the packaging of eukaryotic chromosomes.

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Prokaryotic operons typically include a(n) ________ and a(n) ________ with multiple genes.


A) operator; terminator
B) operator; promoter
C) promoter; repressor
D) inducer; repressor
E) CAP-binding site; inducer

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Which of the following is involved in translation?


A) rRNA only
B) tRNA only
C) mRNA only
D) both mRNA and tRNA
E) mRNA, rRNA, and tRNA are all involved.

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The horizontal transfer process known as transduction


A) involves a virus.
B) requires a pilus.
C) requires a cell to be "competent."
D) requires a plasmid.
E) involves a mutagen.

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Amino acids are delivered in their appropriate order by


A) mRNAs.
B) RNA-induced silencing complexes (RISC) .
C) ribozymes.
D) rRNAs.
E) tRNAs.

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Nucleotide analogs cause frameshift mutations.

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Frederick Griffith discovered


A) transformation.
B) transposons.
C) the lac operon.
D) DNA.
E) conjugation.

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Which of the following is NOT a characteristic of Okazaki fragments?


A) They are checked for accuracy by DNA polymerase III.
B) They make up the lagging strand of replicated DNA.
C) They begin with an RNA primer.
D) They are joined together by DNA ligase.
E) They are longer in eukaryotic cells.

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Which of the following causes mutations by creating thymine dimers?


A) nucleotide analogs
B) nitrous acid
C) ultraviolet light
D) benzopyrene
E) gamma rays

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Which of the following DNA repair processes is most likely to introduce mutations into the repaired DNA?


A) base-excision repair
B) light repair
C) single-strand repair
D) mismatch repair
E) SOS response repair

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A bacterial genome is typically


A) a single linear piece of DNA.
B) multiple linear pieces of DNA.
C) a linear RNA molecule.
D) a single circular DNA molecule.
E) multiple circular DNA molecules.

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