Question 1

Which of the following is not associated with terminal differentiation?

Accepted Answer

A)   Cells assume specific shapes associated with function
B)   It is often controlled by master regulatory genes
C)   Differentiated cells are highly proliferative
D)   Cell fate is controlled by a specific combinations of genes

Question 2

Epidermal skin stem cells reside within the basal layer of the epidermis, just above the basement membrane and the dermis. What is the stem-cell niche for these particular stem cells?

Accepted Answer

A)   The basement membrane
B)   Neighbouring epidermal cells
C)   Sebaceous glands
D)   Sweat glands

Question 3

Which of the following is not true of epigenetic control?

Accepted Answer

A)   It hinges on the methylation status of DNA
B)   It refers to changes in the DNA nucleotide sequence
C)   It involves post-translational modifications to histone proteins
D)   The pattern of modifications on chromatin can be transmitted to daughter cells.

Question 4

Which of the following is not true of somatic cell nuclear transfer?

Accepted Answer

A)   It is used to produce animal clones
B)   A nucleus from an adult differentiated cell is often used
C)   It can be used to create patient-specific stem cells
D)   The resulting embryo is genetically identical to the egg donor

Question 5

Which of the following surrounds a stem cell and maintains its proliferative state and self-renewal capabilities?

Accepted Answer

A)   Stem-cell niche
B)   Stem-cell milieu
C)   Stem-cell marrow
D)   Stem-cell complex A

Question 6

From which group of cells are embryonic stem cells derived?

Accepted Answer

A)   Trophectoderm
B)   Primitive endoderm
C)   Extra-embryonic ectoderm
D)   Inner cell mass

Question 7

Which of the options given is the DNA control region that regulates switching in the beta-family globin genes during development?

Accepted Answer

A)   Globin control region
B)   Locus enhancer region
C)   Globin activation region
D)   Locus control region

Question 8

What is the correct flow of skeletal muscle development in a vertebrate embryo?

Accepted Answer

A)   Myotome - myoblast - myotube - muscle fiber
B)   Myoblast - myotome - myotube - muscle fiber
C)   Myotome - myoblast - muscle fiber - myotube
D)   Myotome - myotube - myoblast - muscle fiber A

Question 9

The epithelial lining of the small intestine is exposed to a harsh environment and undergoes continuous cell loss. In which region of the small intestine do stem cells reside?

Accepted Answer

A)   The goblet
B)   The villus
C)   The mesenchyme
D)   The crypt D

Question 10

Which of the following is not true of the MyoD protein?

Accepted Answer

A)   It promotes downstream muscle-specific transcription factors
B)   It promotes its own production in a positive-feedback loop
C)   Mouse knock-outs lacking MyoD function do not develop skeletal muscle
D)   It is only expressed in muscle precursors and muscle cells

Exam 8: Cell Differentiation Stem Cells

Which of the following is not associated with terminal differentiation?

Correct Answer
verified

Epidermal skin stem cells reside within the basal layer of the epidermis, just above the basement membrane and the dermis. What is the stem-cell niche for these particular stem cells?

Correct Answer
verified

Which of the following is not true of epigenetic control?

Correct Answer
verified

Which of the following is not true of somatic cell nuclear transfer?

Correct Answer
verified

Which of the following surrounds a stem cell and maintains its proliferative state and self-renewal capabilities?

Correct Answer
verified
A

From which group of cells are embryonic stem cells derived?

Correct Answer
verified

Which of the options given is the DNA control region that regulates switching in the beta-family globin genes during development?

Correct Answer
verified

What is the correct flow of skeletal muscle development in a vertebrate embryo?

Correct Answer
verified
A

The epithelial lining of the small intestine is exposed to a harsh environment and undergoes continuous cell loss. In which region of the small intestine do stem cells reside?

Correct Answer
verified
D

Which of the following is not true of the MyoD protein?

Correct Answer
verified

Exam 8: Cell Differentiation Stem Cells

Which of the following is not associated with terminal differentiation?

Correct AnswerverifiedShow Answer

Epidermal skin stem cells reside within the basal layer of the epidermis, just above the basement membrane and the dermis. What is the stem-cell niche for these particular stem cells?

Correct AnswerverifiedShow Answer

Which of the following is not true of epigenetic control?

Correct AnswerverifiedShow Answer

Which of the following is not true of somatic cell nuclear transfer?

Correct AnswerverifiedShow Answer

Which of the following surrounds a stem cell and maintains its proliferative state and self-renewal capabilities?

Correct AnswerverifiedA

From which group of cells are embryonic stem cells derived?

Correct AnswerverifiedShow Answer

Which of the options given is the DNA control region that regulates switching in the beta-family globin genes during development?

Correct AnswerverifiedShow Answer

What is the correct flow of skeletal muscle development in a vertebrate embryo?

Correct AnswerverifiedA

The epithelial lining of the small intestine is exposed to a harsh environment and undergoes continuous cell loss. In which region of the small intestine do stem cells reside?

Correct AnswerverifiedD

Which of the following is not true of the MyoD protein?

Correct AnswerverifiedShow Answer

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified
A

Correct Answer
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Correct Answer
verified

Correct Answer
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A

Correct Answer
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D

Correct Answer
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