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The backbone of the DNA molecule is formed by ________.


A) peptide bonds
B) ribose sugars
C) nitrogenous bases
D) phosphodiester bonds

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The first group of researchers to correctly identify the double-helix structure of DNA were _______.


A) McClintock and Franklin
B) Hershey and Chase
C) Pauling and Avery
D) Watson and Crick

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Frederick Griffith is responsible for discovering what process?


A) Replication
B) Transmission
C) Transformation
D) Transduction

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Adenine and thymine form _______ hydrogen bonds between them, while cytosine and guanine form _______ bonds.


A) 2 , 3
B) 3 , 4
C) 3 , 2
D) 4 , 3

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All living organisms use DNA as the genetic material.

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One strand of DNA is 5' - AGGCCTTA - 3'. What is the opposite strand?


A) 5'-AGGCCTTA-3'
B) 5'-TCCGGAAT-3'
C) 3'-AGGCCTTA-5'
D) 3'-TCCGGAAT-5'

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Which of the following is a correct matching of the researcher with their discovery?


A) Pauling provided information on primary structure in biological molecules.
B) Franklin suggested that DNA was a helix with more than one strand and that there were about 10 bases per turn of the DNA.
C) Watson and Crick collected a large amount of X-ray data on the structure of DNA.
D) Chargaff demonstrated that the adenine and cytosine bases and the uracil and guanine bases interacted in some manner.

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Avery used the enzyme _______ to remove the proteins from the cell extracts.


A) protease
B) DNase
C) RNase
D) All of the answers are correct

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The building blocks of DNA are called _________.


A) amino acids
B) codons
C) nucleotides
D) alleles

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What were the conclusions of Franklin's work regarding the structure of DNA?


A) It did not have a helical structure
B) The helix had more than one strand
C) The helix contained about 1 bases per turn
D) The helix had only one strand

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What was the conclusion of the Hershey-Chase experiments?


A) Their results suggested the presence of a transforming principle.
B) Their results suggested that DNA is a double helix
C) Their results suggested that A+G=T+C
D) Their results suggested that the DNA is the genetic material

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The pyrimidine bases are _______.


A) cytosine, thymine, and uracil
B) adenine and guanine
C) adenine and thymine
D) cytosine and guanine

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A purine on one strand of the DNA is always paired with a pyrimidine on the other strand.

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What is the most complex structure DNA can form?


A) individual nucleotides
B) a folded and bended double helix
C) a single strand of DNA
D) a DNA double helix

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The idea that the adenine and thymine bases of the DNA interact in some manner was first proposed by _______.


A) Watson and Crick
B) Franklin
C) Pauling
D) Chargaff

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Which base is not found in DNA?


A) Cytosine
B) Guanine
C) Thymidine
D) Adenine
E) Uracil

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These individuals determined that DNA was responsible for the process of transduction in T2 phage.


A) Hershey and Chase
B) Avery, Macleod, and McCarty
C) Watson and Crick
D) Creighton and McClintock

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The researcher(s) who initially used X-ray diffraction to gather information on the DNA molecule was ______.


A) Franklin
B) Watson and Crick
C) Hershey and Chase
D) Pauling
E) Chargaff

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How does DNA differ from RNA?


A) RNA uses only purines
B) RNA uses a different five-carbon sugar
C) RNA has a contains different sized phosphate groups
D) RNA has multiple bases attached to the sugar

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In the Hershey-Chase experiments, the protein coat of the bacteriophage was labeled with the 32P radioisotope.

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