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List at least four difficulties associated with developing a replacement organ that scientists have had to overcome,and still have yet to overcome.

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Scientists do not always know where stem...

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Specialized cells called _______ are found in most tissues.These cells divide to give rise to more cells of that tissue.


A) mother cells
B) stem cells
C) regenerative cells
D) core cells
E) embryonic cells

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What was the major discovery in tissue engineering that advanced the field to where it is today?


A) the use of scaffolds to grow organs
B) tissue antirejection techniques
C) stem-cell isolation from adult tissues
D) A and C
E) All of the above.

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Embryonic stem cells are harvested from the inner cell mass.If this inner cell mass is allowed to continue to develop without harvesting,what would it normally become?


A) a fetus
B) a larger mass of cells, never forming a complete structure
C) adult stem cells only
D) the tissues, organs, and systems of the body
E) A and D

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Describe the three methods of creating embryonic stem cells.Which one(s)is/are likely to be the most controversial and why?

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Embryonic stem cells can be made
(1)by ...

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Explain why growing your own organs is biologically better than implanting an organ from a donor.

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Your body will recognize organs grown fr...

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How can a blastocyst,which is basically a mass of cells,develop into different tissues,organs,systems,and ultimately a fetus?


A) Chemicals enter the cells, causing them to become different tissues.
B) Chemical signals cause the production of genes.
C) Chemical signals cause the regulation of genes and production of particular proteins.
D) Chemical signals cause the regulation of proteins that will produce the appropriate genes.
E) Chemical signals cause all cells to develop into one type of organ that splits off into all the organs of the body.

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To engineer a human bladder requires


A) a bladder biopsy, tissue growth on a scaffold, and transplant surgery.
B) stem cell isolation from a bladder biopsy and transplant surgery.
C) a bladder biopsy, stem cell isolation and growth on a scaffold, and transplant surgery.
D) a donor bladder, growth on a scaffold, and replacement surgery.
E) surgery for removal of the bladder and replacement with a donor bladder.

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Differential gene expression is


A) use of a unique set of genes in each cell type.
B) the pathway to a cells specialization.
C) required for different cell types.
D) required for a cellโ€™s function and physical shape.
E) All of the above.

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List the following in order from LEAST to MOST specialized cells. A) inner cell mass from blastocyst A) liver cells A) preblastocyst cells A) somatic stem cells

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Why would you need to isolate more than one type of stem cell when growing a replacement organ?


A) More than one type of stem cell is grown in case one type does not survive.
B) Growing replacement organs requires at least three types of stem cells.
C) Different tissues have different stem cells.
D) Organs are composed of more than one type of tissue.
E) C and D

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The formation of an organ through the use of stem cells differentiated into multiple cell types.However,which of the following presents a hurdle to regenerating a new organ to replace a defective one?


A) Many organs contain multiple specialized cell types in an intricate design.
B) Nerve innervation is necessary for the proper function of some organs.
C) Proper blood supply to all the regenerated cells is necessary for the survival of organs.
D) A and C
E) All of the above.

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What is the primary hurdle in the healing process of humans that must be bypassed when compared with the tissue regeneration of a salamander?


A) organ rejection
B) tissue development
C) development of scar tissue
D) regeneration of a new tissue
E) differential regeneration

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Why are some cells in your body younger than others? What determines how often a particular cell type needs to be replaced? Name one cell type that is regenerated frequently and one cell type that is rarely replaced.

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Cells that are used a lot or are exposed...

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As every cell in our body has the same genome,what is the basic difference between cells with unique functions?


A) stem cells
B) the cellโ€™s genome
C) mitosis
D) cell differentiation
E) gene expression

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Which of the following cell types is MOST differentiated?


A) zygote cell
B) bone-marrow cell
C) neuron from the cerebral cortex
D) neural stem cell
E) mesenchymal stem cell

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Why do researchers think embryonic stem cells offer more hope than adult stem cells?

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Theoretically,an embryonic stem cell can...

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How can embryonic stem cells be created in a lab?


A) The nucleus of an egg is transplanted into a sperm, which artificially fertilizes a new egg.
B) The nucleus of an egg is removed, and a new nucleus from an adult donor cell is transplanted into the egg.
C) The nucleus of a sperm is transplanted into an egg.
D) The nucleus of an egg is removed, and a new nucleus from a sperm is transplanted into the egg.
E) The nucleus of an egg is transplanted into an adult donor cell.

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Induced pluripotent stem cells have been created by


A) inserting four genes into a differentiated skin cell.
B) inserting 18 genes into an embryonic stem cell.
C) starting with a blastocyst cell.
D) inserting "dedifferentiating" proteins into an adult stem cell.
E) None of the above.

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The difficulties involved in growing a replacement organ include all of the following,EXCEPT


A) scientists have not yet figured out how to make biodegradable scaffolds on which to grow the tissues.
B) organs are made from many different types of stem cells.
C) the larger the organ, the more complex it is.
D) most organs require other associated tissues, such as specialized nerves and muscles.
E) usually a biopsy is required to obtain the stem cells, thus resulting in multiple surgeries.

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