A) Determining what restriction sites are present in a fragment of DNA
B) Identifying a promoter sequence
C) Identifying splice donor and acceptor sites
D) Identify related sequences to a given DNA sequence in the Genbank database
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A) Proteins may be modified by covalent addition of a variety of molecules
B) Not all genes are expressed in all cells at the same time
C) Many coding genes are transcribe into mRNA which can be alternatively spliced, and those transcripts produce different proteins so the ratio of the number of protein molecules the number of genes is greater than 1.
D) The total amount of protein in a cell as measured by mass is always greater than the total amount of DNA.
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A) Search-by-signal
B) Search-by-content
C) Search-by-identity
D) Search-by-recognition
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A) by charge only
B) primarily by molecular mass
C) by size only
D) net charge
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A) Orthologs
B) Paralogs
C) Polylogs
D) Homologs
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A) Related genes
B) Paralogs
C) Gene family
D) Orthologs
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D
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A) Phosphorylation of some amino acid residues.
B) mRNA editing resulting in a slightly different amino acid sequence.
C) Alternative exon usage.
D) Proteolytic processing.
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A) Structural genomics
B) Functional genomics
C) Proteomics
D) Bioinformatics
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A) Western blots
B) Antibody microarrays
C) Two-dimensional gel electrophoresis
D) Functional protein microarrays
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False
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A) To examine patterns of protein expression under various environmental conditions
B) To establish levels of genetic variation
C) To determine the mass of a gene
D) To identify the amount of a specific transcription factor in a cell.
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A) they can be used to develop models of human disease.
B) they identify DNA binding proteins
C) they limit mRNA production both from the knockout as well as the normal allele in diploids.
D) only genes that are actively transcribed in the embryo are susceptible to being knocked out.
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A
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A) A large collection of files stored in one place.
B) A small collection of files that are stored in different places
C) Files that are only used by the BLAST program
D) A large collection of files that are not annotated.
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A) The probe hybridized to the sequences present in that spot
B) The probe did not hybridize to that particular gene
C) The experiment was not conducted correctly
D) That the probe was non-specifically trapped by the material present in the spot.
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A) assay the use of substrates by different enzymes.
B) determine mRNA folding patterns
C) identify DNA sequences bound by specific proteins.
D) identify protein-protein interactions.
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A) X-ray crystallography
B) Nuclear magnetic resonance
C) Mass spectrometry
D) The ChIP assay
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A) Alternative splicing
B) Proteins are constantly being synthesized and degraded.
C) Each protein has a specific function which are quite varied while the genes in the genome are only transcribed
D) Each protein has multiple functional domains while each gene consists of three basic parts.
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A) Bioinformatics
B) PCR reactions
C) DNA microarrays
D) The BLAST program
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